Impact is a food supplement made from bovine colostrum powder, with added lactoferrin, lactoperoxidase, whey protein, omega-3 & 6 fatty acids, vitamins and minerals. Feed Impact to newborn mammals as a colostrum replacement or to marsupial joeys as an adjunct to milk replacers.
Colostrum is the first milk produced after birth. It is high in protein, much of which is immunoglobulin. Immunoglobulins provide immunity against pathogenic micro-organisms such as bacteria and viruses.
Most animals are born without immunity and initially acquire their immunoglobulins from colostrum. Newborns that do not receive colostrum have a weakened immune system and increased risk of infection and mortality. Colostrum contains other proteins with antibacterial activity such as Lactoferrin, Lactoperoxidase and Lysozyme. These act to inhibit the colonisation of the intestine by pathogenic
micro-organisms via the following mechanisms:
Lactoferrin binds iron and facilitates its uptake from the intestine2. Due to its iron-binding capacity, lactoferrin inhibits many micro-organisms that require iron for growth3,4. When Lactoferrin is hydrolysed by gastric enzymes it releases a peptide that is highly bactericidal to several species of pathogenic organisms5.
Lactoperoxidase is bacteriostatic to a wide range of bacteria in the presence of thiocyanate and
hydrogen peroxide-generating enzymes in the gut3,4.
Lysozyme destroys bacteria by hydrolysing the muramic acid in the bacterial cell wall3,4.
In most mammals, colostrum is only produced for a short time after birth. During this time the intestine is open to the absorption of the large immunoglobulin molecules. However, intestinal closure occurs rapidly as the mammary secretions change from colostrum to normal milk1. This occurs within 24 hours in cows, horses, cats & dogs, 2 days in guinea pigs and 3 days in pigs. Feeding milk too early may hasten intestinal closure, and thus reduce the ability to absorb immunoglobulins.
Bovine colostrum provides immunity against a wide range of pathogens that are present in the environment
(eg rotavirus, which can cause acute diarrhoea6). As these pathogens are common to most animal species, bovine colostrum has been successfully used to improve the immune response in a diverse range of
First 12 hours after birth | Prepare an Impact Dose as described above and feed å_ of the amount every 2 hours. Do not feed milk during this time.
12 to 48 hours after birth | Commence feeding milk. Prepare an Impact Dose as described above and feed å_ of the amount every 4 hours, in between milk feeds.
Do not mix or feed Impact with milk.
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